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MONTE CARLO ESTIMATION OF DOSE DIFFERENCE IN LUNG FROM 192Ir BRACHYTHERAPY DUE TO TISSUE INHOMOGENEITY.
MedLine Citation:
PMID:  21831865     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Lung brachytherapy using high-dose rate (192)Ir technique is a well-established technique of radiation therapy. However, many commercial treatment planning systems do not have the ability to consider the inhomogeneity of lung in relation to normal tissue. Under such circumstances dose calculations for tissues and organs at risk close to the target are inaccurate. The purpose of the current study was to estimate the dose difference due to tissue inhomogeneity using the Monte Carlo simulation code MCNP-5. Results showed that there was a relative sub dosage by treatment planning systems calculations in neighbouring tissues around the radioactive source due to inhomogeneity ignorance. The presence of lung instead of normal tissue resulted in an increase in relative dose, which approached 8 % at 4-cm distance from the source. Additionally, the relative increase was small for the lung (2.1 %) and larger for organs at risk such as the heart (6.8 %) and bone marrow (7.6 %).
Authors:
G Gialousis; A Dimitriadis; E Yakoumakis
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-9
Journal Detail:
Title:  Radiation protection dosimetry     Volume:  -     ISSN:  1742-3406     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8109958     Medline TA:  Radiat Prot Dosimetry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Medical Physics Department, IASSO Hospital, 37-39 Kifissias Str., Maroussi 15123, Athens, Greece.
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