Document Detail

Monte Carlo study of radial energy deposition from primary and secondary particles for narrow and large proton beamlet source models.
MedLine Citation:
PMID:  22617113     Owner:  NLM     Status:  MEDLINE    
In spot-scanning intensity-modulated proton therapy, numerous unmodulated proton beam spots are delivered over a target volume to produce a prescribed dose distribution. To accurately model field size-dependent output factors for beam spots, the energy deposition at positions radial to the central axis of the beam must be characterized. In this study, we determined the difference in the central axis dose for spot-scanned fields that results from secondary particle doses by investigating energy deposition radial to the proton beam central axis resulting from primary protons and secondary particles for mathematical point source and distributed source models. The largest difference in the central axis dose from secondary particles resulting from the use of a mathematical point source and a distributed source model was approximately 0.43%. Thus, we conclude that the central axis dose for a spot-scanned field is effectively independent of the source model used to calculate the secondary particle dose.
Christopher R Peeler; Uwe Titt
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-05-23
Journal Detail:
Title:  Physics in medicine and biology     Volume:  57     ISSN:  1361-6560     ISO Abbreviation:  Phys Med Biol     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-07     Completed Date:  2012-10-04     Revised Date:  2013-06-25    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  3785-92     Citation Subset:  IM    
The University of Texas Graduate School of Biomedical Sciences at Houston, 6767 Bertner Avenue, S3.8344, Houston, TX 77030, USA.
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MeSH Terms
Models, Theoretical*
Monte Carlo Method*
Phantoms, Imaging
Protons / therapeutic use*
Radiotherapy Dosage
Grant Support
Reg. No./Substance:
0/Protons; 7732-18-5/Water

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