Document Detail


Monte Carlo simulation of electron beams generated by a 12 MeV dedicated mobile IORT accelerator.
MedLine Citation:
PMID:  21725139     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The aim of this study was to investigate the dosimetric characteristics of the electron beams generated by the light intraoperative accelerator, Liac® (SORDINA, Italy), using Monte Carlo (MC) calculations. Moreover we investigated the possibility of characterizing the Liac® dosimetry with a minimal set of dosimetric data. In fact accelerator commissioning requires measurements of both percentage depth doses (PDDs) and off-axis profiles for all the possible combinations of energy, applicator diameter and bevelled angle. The Liac® geometry and water phantom were simulated in a typical measurement setup, using the MC code EGSnrc/BEAMnrc. A simulated annealing optimization algorithm was used in order to find the optimal non-monoenergetic spectrum of the initial electron beam that minimizes the differences between calculated and measured PDDs. We have concluded that, for each investigated nominal energy beam, only the PDDs of applicators with diameters of 30, 70 and 100 mm and the PDD without an applicator were needed to find the optimal spectra. Finally, the output factors of the entire set of applicator diameters/bevelled angles were calculated. The differences between calculated and experimental output factors were better than 2%, with the exception of the smallest applicator which gave differences between 3% and 4% for all energies. The code turned out to be useful for checking the experimental data from various Liac® beams and will be the basis for developing a tool based on MC simulation to support the medical physicist in the commissioning phase.
Authors:
G Iaccarino; L Strigari; M D'Andrea; L Bellesi; G Felici; A Ciccotelli; M Benassi; A Soriani
Related Documents :
21968209 - Effect of nitro groups on the photo physical properties of benzimidazolone: a solvatoch...
18620259 - Ultrastructure of feeding in the karyorelictean ciliate tracheloraphis examined by scan...
21817389 - Backscattering coefficients for low energy positrons and electrons impinging on bulk so...
8440569 - Ultrastructure of trichophyton violaceum.
12663949 - Research of the entry of rare earth elements eu3+ and la3+ into plant cell.
21817279 - Percolation limit and stability conditions for the spin glass state in the spinel famil...
25359809 - Direct observations of local electronic states in an al-based quasicrystal by stem-eels.
20867409 - Edge dynamics in a quantum spin hall state: effects from rashba spin-orbit interaction.
21469889 - Two-dimensional and three-dimensional fermi surfaces of superconducting bafe_{2}(as_{1-...
Publication Detail:
Type:  Journal Article     Date:  2011-07-01
Journal Detail:
Title:  Physics in medicine and biology     Volume:  56     ISSN:  1361-6560     ISO Abbreviation:  Phys Med Biol     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  4579-96     Citation Subset:  IM    
Affiliation:
Laboratory of Medical Physics, Istituto Regina Elena, via Elio Chianesi 53, 00144, Rome, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Targeting invadopodia to block breast cancer metastasis.
Next Document:  Comparison of manual and automatic segmentation methods for brain structures in the presence of spac...