Document Detail

Monozygotic twins non-concordant for oligomeganephronic renal hypoplasia: artery-vein placental shunting as a possible pathogenetic mechanism.
MedLine Citation:
PMID:  3955916     Owner:  NLM     Status:  MEDLINE    
The etiology and pathogenesis of oligomeganephronic renal hypoplasia (OMN) are not known. In the present paper a second case of monozygotic twins non-concordant for OMN is described. It is hypothesized that one of the mechanisms which have been proposed to explain structural defects in monozygotic twins, namely placental artery-vein shunting, may have been involved in the pathogenesis of OMN in these patients. In OMN in general vascular abnormalities may have to be considered as a pathogenetic mechanism.
K J Van Acker; A M Roodhooft; K Melis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  25     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-05-02     Completed Date:  1986-05-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  165-8     Citation Subset:  IM    
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MeSH Terms
Diseases in Twins*
Kidney / abnormalities*
Kidney Failure, Chronic / etiology,  genetics*
Nephrons / abnormalities
Twins, Monozygotic

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