Document Detail

Monozygotic twins in infertile patients with advanced maternal age: case reports and review of the literature.
MedLine Citation:
PMID:  19608163     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report two cases of successful monozygotic twin pregnancies in women undergoing infertility treatment and to review possible etiologic factors. DESIGN: Case report and review of the literature. SETTING: University of Toronto-affiliated infertility clinic. PATIENT(S): A 43-year-old woman and a 44-year-old woman with history of secondary infertility. INTERVENTION(S): In vitro fertilization and ET. MAIN OUTCOME MEASURE(S): Monozygotic twin pregnancy. RESULT(S): Delivery of two sets of monozygotic twins. CONCLUSION(S): The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. Both patients reported here were aged >40 years and underwent assisted reproduction procedures, including high-dose gonadotropin stimulation, embryo culture, and, in case 2, intracytoplasmic sperm injection plus assisted hatching.
Navid Esfandiari; Monica Kapoor; Hasan Burjaq; Paul Chang; Lynda Gotlieb; Robert F Casper
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-07-15
Journal Detail:
Title:  Fertility and sterility     Volume:  92     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-31     Completed Date:  2009-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1168.e9-1168.e12     Citation Subset:  IM    
Toronto Centre for Advanced Reproductive Technology, University of Toronto, Toronto, Ontario, Canada.
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MeSH Terms
Infertility, Female / therapy*
Maternal Age
Pregnancy Outcome*
Reproductive Techniques, Assisted*
Risk Factors
Twins, Monozygotic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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