Document Detail

Monozygotic triplet pregnancy following egg donation and transfer of single frozen-thawed embryo.
MedLine Citation:
PMID:  17628555     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe a case of monozygotic triplet pregnancy following egg donation and the transfer of a single frozen-thawed embryo. DESIGN: Case report. SETTING: District general hospital and regional department of fetal medicine in northeast England. PATIENT(S): A 38-year-old woman with a 2-year history of primary infertility due to severe endometriosis and poor ovarian reserve who conceived after egg donation and transfer of a single frozen-thawed embryo. INTERVENTION(S): Transfer of a single frozen-thawed embryo and delivery of three identical female infants by emergency caesarean section because of preterm labor at 32 weeks' gestation. MAIN OUTCOME MEASURE(S): Review of effect of assisted conception on monozygotic twinning rates. RESULT(S): Healthy outcome for all three infants. CONCLUSION(S): Assisted reproductive treatments may lead to disturbances in zona pellucida architecture and an increase in monozygotic twinning rates. Couples need to be informed of this and the increased risks associated with these pregnancies before they begin with treatment.
Radwan Faraj; Isaac Evbuomwan; Stephen Sturgiss; Ian Aird
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-12
Journal Detail:
Title:  Fertility and sterility     Volume:  89     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-19     Completed Date:  2008-06-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1260.e9-12     Citation Subset:  IM    
Centre for Assisted Reproduction, Queen Elizabeth Hospital, Gateshead, United Kingdom.
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MeSH Terms
Embryo Transfer / methods*
Endometriosis / complications
Infertility, Female / etiology,  therapy*
Oocyte Donation / methods*
Pregnancy Outcome
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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