| Monozygotic triplet pregnancies after single blastocyst transfer: two cases and literature review. | |
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MedLine Citation:
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PMID: 20638341 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Following IVF, single blastocyst transfer has been thought to reduce the risks of high-order multiple pregnancies. This is a report of two cases of monozygotic triplet pregnancies after single blastocyst transfer and a review of the current concepts of the pathogenesis of multiple monozygotic pregnancies as well as the options for managing these high-risk pregnancies. Both cases were reduced to a twin pregnancy by selective cord coagulation at 15-16 weeks. Whereas one patient had uneventful pregnancy until labour was induced for growth arrest and cord Doppler abnormalities in one twin, the other developed a severe twin-to-twin transfusion syndrome which required fetoscopic laser surgery at 21 weeks. In both cases, healthy twins were delivered by Caesarean section at 34.5 and 34 weeks, respectively. As the predictors of their occurrence are not fully understood, patients should be informed of the risks of monozygotic pregnancies after single blastocyst transfer. |
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Authors:
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Lionel Dessolle; Dalila Allaoua; Thomas Fréour; Claudine Le Vaillant; Henri-Jean Philippe; Miguel Jean; Paul Barrière |
Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2010-04-24 |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 21 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-12-16 Revised Date: 2011-12-06 |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: Netherlands |
Other Details:
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Languages: eng Pagination: 283-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Service de biologie et médecine de la reproduction, Centre Hospitalier Universitaire de Nantes, 38, Bd Jean Monnet, 44093 Nantes Cedex 1, France. lionel.dessolle@yahoo.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Embryo Transfer / adverse effects Female Fetofetal Transfusion* / etiology Humans Infant, Newborn Male Pregnancy Pregnancy Reduction, Multifetal Pregnancy, Multiple* / genetics Risk Factors Single Embryo Transfer* / adverse effects Triplets* / genetics Twinning, Monozygotic* / genetics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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