Document Detail

Monounsaturated oils do not all have the same effect on plasma cholesterol.
MedLine Citation:
PMID:  9630379     Owner:  NLM     Status:  MEDLINE    
Evidence assembled here indicates that when olive oil forms a major part of dietary fat in controlled human experiments, total and LDL-cholesterols are somewhat higher than when the same amount of fat is one of the modern predominantly monounsaturated oils: low erucic rapeseed or high oleic sunflower oil. Oils rich in monounsaturated fatty acids thus do not all have the same effect on plasma cholesterol. This phenomenon is explicable by consideration of the content of other fatty acids and the non-saponifiable fractions of the different monounsaturated oils. It helps to explain the discrepancy that has existed between the classic experiments (using olive oil), which found monounsaturated oils 'neutral', and some of the more recent experiments which found them more cholesterol-lowering than carbohydrates. Four published meta-analyses are reviewed. The three which included most of the published experiments show that monounsaturated fatty acids (MUFA) have less plasma cholesterol-lowering effect than polyunsaturated fatty acids.
A S Truswell; N Choudhury
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  52     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-08-04     Completed Date:  1998-08-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  312-5     Citation Subset:  IM    
Human Nutrition Unit, University of Sydney, NSW, Australia.
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MeSH Terms
Cholesterol / blood*
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Dietary Fats, Unsaturated / pharmacology*
Erucic Acids / pharmacology
Fatty Acids, Monounsaturated / administration & dosage,  pharmacology*
Oleic Acid / pharmacology
Plant Oils / pharmacology
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Dietary Fats, Unsaturated; 0/Erucic Acids; 0/Fatty Acids, Monounsaturated; 0/Plant Oils; 1072-39-5/erucic acid; 112-80-1/Oleic Acid; 120962-03-0/canola oil; 57-88-5/Cholesterol; 8001-21-6/sunflower seed oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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