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Mononuclear phagocyte depletion strategies in models of acute kidney disease: what are they trying to tell us?
MedLine Citation:
PMID:  23018825     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Mononuclear phagocytes (macrophages, dendritic cells, and monocytes) play a complex role in kidney disease. Techniques for selectively depleting them in rodents have made important contributions but have also generated some contradictory results. Ferenbach et al. report that two widely used mononuclear phagocyte depletion techniques differentially affect early severity of renal ischemia/reperfusion injury and provide evidence that this may be due to a residual, protective subset that persists in the kidney after one of the two techniques.
Authors:
Matthew D Griffin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kidney international     Volume:  82     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  835-7     Citation Subset:  IM    
Affiliation:
Regenerative Medicine Institute (REMEDI), National Centre for Biomedical Engineering Science (NCBES) and School of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Ireland.
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