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Monodisperse NaYbF(4) : Tm(3+)/NaGdF(4) core/shell nanocrystals with near-infrared to near-infrared upconversion photoluminescence and magnetic resonance properties.
MedLine Citation:
PMID:  21373678     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We report core/shell NaYbF(4) : Tm(3+)/NaGdF(4) nanocrystals to be used as probes for bimodal near infrared to near infrared (NIR-to-NIR) upconversion photoluminescence (UCPL) and magnetic resonance (MR) imaging. The NaYbF(4) : Tm(3+) nanocrystals were previously reported to produce the intense NIR-to-NIR UCPL peaked at ∼800 nm under excitation at ∼975 nm. We have found that the growth of a NaGdF(4) shell on surface of the NaYbF(4) : Tm(3+) nanocrystals results in the increase in the intensity of UCPL of Tm(3+) ions by about 3 times. Unlike biexponential PL decay of NaYbF(4) : Tm(3+) nanocrystals, the PL decay of NaYbF(4) : Tm(3+)/NaGdF(4) core/shell nanocrystals is single exponential and of longer lifetime due to the suppression of surface quenching effects for Tm(3+) PL. The growth of a NaGdF(4) shell on surface of the NaYbF(4) : Tm(3+) nanocrystals also provides high MR relaxivity from paramagnetic Gd(3+) ions contained in the shell. The T1-weighted MR signal of the (NaYbF(4):2% Tm(3+))/NaGdF(4) nanoparticles was measured to be about 2.6 mM(-1)s(-1). Due to the combined presence of efficient optical and MR imaging capabilities, nanoprobes based on NaYbF(4) : Tm(3+)/NaGdF(4) fluoride nanophosphors can be considered as a promising platform for simultaneous bimodal PL and MR bioimaging.
Authors:
Guanying Chen; Tymish Y Ohulchanskyy; Wing Cheung Law; Hans Agren; Paras N Prasad
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-3
Journal Detail:
Title:  Nanoscale     Volume:  -     ISSN:  2040-3372     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101525249     Medline TA:  Nanoscale     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Institute for Lasers, Photonics, and Biophotonics, The State University of New York at Buffalo, Buffalo, New York 14260, USA. tyo2@buffalo.edu pnprasad@buffalo.edu.
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