Document Detail

Monoclonal gammopathy (IgM-kappa) in a patient with Burkitt's lymphoma. Case report and literature review.
MedLine Citation:
PMID:  6404235     Owner:  NLM     Status:  MEDLINE    
A monoclonal immunoglobulin, IgM-kappa, was detected in the serum of a patient with Burkitt's lymphoma. This rarely reported finding raises the possibility that undifferentiated neoplastic lymphoreticular cells in this disorder have the capacity to synthesize immunoglobulins. Gel-exclusion and ion-exchange column chromatography, as well as immunofixation, allowed for heavy- and light-chain characterization of the subtle monoclonal component.
A H Braunstein; D F Keren
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  107     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Protein Electrophoresis
Burkitt Lymphoma / complications,  immunology*,  pathology
Hypergammaglobulinemia / complications,  immunology*,  pathology
Immunoglobulin Light Chains* / analysis
Immunoglobulin M* / analysis
Immunoglobulin kappa-Chains* / analysis
Reg. No./Substance:
0/Immunoglobulin Light Chains; 0/Immunoglobulin M; 0/Immunoglobulin kappa-Chains

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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