Document Detail


Monoclonal antibodies to the two most basic papaya proteinases.
MedLine Citation:
PMID:  3545314     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The proteinases from Carica papaya include papain, isoenzymes of chymopapain and two proteinases A and B distinguished by their unusually high pI. The identity of one of the most basic proteinases has been questioned. The present report describes the preparation and characterisation of two monoclonal antibodies that react specifically with papaya proteinases A and B respectively and a third that identifies a common structural feature found in papain and proteinase A.
Authors:
P W Goodenough; P J Kilshaw; F McEwan; A J Owen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bioscience reports     Volume:  6     ISSN:  0144-8463     ISO Abbreviation:  Biosci. Rep.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1987-03-31     Completed Date:  1987-03-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8102797     Medline TA:  Biosci Rep     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  759-66     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / immunology*
Antibody Specificity
Chymopapain / immunology
Cysteine Endopeptidases*
Endopeptidases / immunology*
Immunosorbent Techniques
Isoelectric Point
Molecular Weight
Papain / immunology
Plant Proteins*
Plants / enzymology*
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Plant Proteins; EC 3.4.-/Endopeptidases; EC 3.4.22.-/Cysteine Endopeptidases; EC 3.4.22.2/Papain; EC 3.4.22.25/glycyl endopeptidase; EC 3.4.22.30/caricain; EC 3.4.22.6/Chymopapain

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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