Document Detail

Monoclonal antibodies (Mabs) in head and neck cancer.
MedLine Citation:
PMID:  3534285     Owner:  NLM     Status:  MEDLINE    
The development of monoclonal antibodies (Mabs) represents a major contribution of immunology to the study of head and neck cancer. The interest of the otolaryngologist in this new field is quite recent, but our knowledge of cancer and other immunoproliferative disorders will exponentially expand with the characterization of tumor-associated antigens of squamous cell carcinomas. The author reviews briefly the technique for producing monoclonal antibodies and presents an overview of the application of Mabs to clinical medicine, oncology and, more specifically, head and neck cancer. Very few contributions have been made in head and neck cancer, but the field of Mabs will significantly alter our diagnostic and therapeutic armamentarium.
J F Poliquin; L G Filion
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of otolaryngology     Volume:  15     ISSN:  0381-6605     ISO Abbreviation:  J Otolaryngol     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-12-17     Completed Date:  1986-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7610513     Medline TA:  J Otolaryngol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  289-92     Citation Subset:  IM    
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MeSH Terms
Antibodies, Monoclonal / analysis*
Antigens, Neoplasm / immunology
Carcinoma, Squamous Cell / immunology*
Head and Neck Neoplasms / immunology*
Hybridomas / immunology
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Antigens, Neoplasm

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