| Monochorionic twin pregnancy: screening, pathogenesis of complications and management in the era of microinvasive fetal surgery. | |
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MedLine Citation:
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PMID: 20629496 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The management of monochorionic (MC) twin pregnancies varies in different medical centers. This paper compares screening methods to predict the complications of the MC twin pregnancy and different treatment methods. METHODS: We performed a literature search without language restriction in Cochrane library and PubMed (1970-2009). Case series and cohort screening studies, pathogenesis and management of complications of MC pregnancy were included. RESULTS: Elevated risk for intrauterine fetal death (IUFD) and twin-to-twin transfusion syndrome (TTTS) can be detected sonographically. Monitoring of MC pregnancies at increased risk and regular training sessions for the operating team combined with reduced fetoscopic amniotic membrane damage increase fetal survival rate from laser coagulation to nearly 100% for at least one fetus and to 90% for both. CONCLUSION: Monitoring of MC pregnancies at increased risk and laser treatment of TTTS in medical centers with sufficient experience might improve neonatal outcome. |
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Authors:
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Michael Tchirikov |
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Publication Detail:
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Type: Journal Article; Review; Twin Study |
Journal Detail:
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Title: Journal of perinatal medicine Volume: 38 ISSN: 1619-3997 ISO Abbreviation: J Perinat Med Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-03 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0361031 Medline TA: J Perinat Med Country: Germany |
Other Details:
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Languages: eng Pagination: 451-9 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Fetal Medicine, Clinic of Obstetrics and Gynecology, University Medical Center of Johannes Gutenberg University Mainz, Mainz, Germany. tchirikov@uni-mainz.de |
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| MeSH Terms | |
Descriptor/Qualifier:
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Amnion
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ultrasonography Chorion / ultrasonography Female Fetal Growth Retardation / etiology, therapy Fetal Therapies / instrumentation, methods* Fetofetal Transfusion / diagnosis, etiology, therapy Humans Infant, Newborn Laser Coagulation / instrumentation, methods Male Models, Biological Pregnancy Pregnancy Complications / diagnosis*, etiology, therapy* Pregnancy, Multiple* Prenatal Diagnosis Twins, Monozygotic* |
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