| Monoamine oxidase inhibitor dietary restrictions: what are we asking patients to give up? | |
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MedLine Citation:
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PMID: 7737959 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Though the list of possible indications for monoamine oxidase inhibitors (MAOIs) continues to expand, many psychiatrists remain hesitant about prescribing MAOIs, citing concerns about dietary prohibitions and hypertensive reactions. Data about psychiatric patients' frequency of consumption of foods, beverages, and medications prohibited during MAOI use are lacking. METHOD: We conducted a survey of 139 psychiatric patients admitted to either an inpatient unit specializing in the treatment of mood disorders or an outpatient anxiety disorders clinic specializing in the treatment of social phobia. At inclusion, patients were not being treated with MAOIs, although they might have received such treatment afterward. All patients completed a self-report questionnaire created for this study to ascertain their consumption of food, beverage, and medication items frequently found on MAOI diet lists. Demographic and diagnostic information was also recorded. RESULTS: The most frequently used high-risk items were the hard cheeses. Ninety percent of patients reported daily or weekly consumption of some food containing cheese, while less than 1% of patients reported never eating hard cheese. Yeast products, dry sausage, corned beef, broad beans, sauerkraut, and beer were used at least monthly by more than 50% of patients. Of the intermediate-risk foods, chocolate was the most frequently consumed, with almost 30% of the patients eating some chocolate daily. Over 40% of patients reported using over-the-counter cold preparations on a monthly basis. CONCLUSION: A wide variety of tyramine-containing foods and contraindicated medications were commonly used by our patients prior to evaluation for possible MAOI pharmacotherapy. The number and diversity of frequently consumed items do not support recommendations to reduce the breadth of restrictions in MAOI diets. Individually targeted dietary assessment and education are recommended to reduce the risks of prescribing MAOIs. |
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Authors:
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R A Sweet; E J Brown; R G Heimberg; L Ciafre; D M Scanga; J R Cornelius; S Dube; K M Forsyth; C S Holt |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of clinical psychiatry Volume: 56 ISSN: 0160-6689 ISO Abbreviation: J Clin Psychiatry Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-06-08 Completed Date: 1995-06-08 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7801243 Medline TA: J Clin Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 196-201 Citation Subset: IM |
Affiliation:
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Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Beverages / adverse effects Cheese / adverse effects Depressive Disorder / drug therapy, psychology Diet Surveys* Drug Interactions Female Food / adverse effects Food Habits* Food, Formulated / utilization Humans Hypertension / chemically induced Male Monoamine Oxidase Inhibitors / administration & dosage*, adverse effects Nonprescription Drugs / administration & dosage, adverse effects Phobic Disorders / drug therapy, psychology Questionnaires Risk Assessment |
| Grant Support | |
ID/Acronym/Agency:
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MH-01153/MH/NIMH NIH HHS; MH-30915/MH/NIMH NIH HHS; MH-44119/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Monoamine Oxidase Inhibitors; 0/Nonprescription Drugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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