Document Detail

Monkey lateral hypothalamic neuron response to sight of food, and during bar press and ingestion.
MedLine Citation:
PMID:  7207875     Owner:  NLM     Status:  MEDLINE    
Unit activity of 144 lateral hypothalamus (LHA) neurons was analyzed in monkey during bar pressing feeding behavior. Eighteen neurons responded only when the animal saw food, and 23 responded only during ingestion of food. Ten responded at both the sight of food and throughout the bar pressing and ingestion periods, even in high fixed ratio schedules. Three neurons responded, not at the sight of food, but at the sight of non-food. Nineteen out of a total of 54 of the above responding neurons were studied for response to differences between food and non-food. Eight responded similarly at the sight of both food and non-food, while 11 responded differently. Responses during the ingestion period were strong and lasted longer than 5--10 sec. The data indicate that some LHA neurons are involved in the discrimination of food, the drive to obtain it and the perception of reward.
T Ono; H Nishino; K Sasaki; M Fukuda; K I Muramoto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroscience letters     Volume:  21     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  1981 Jan 
Date Detail:
Created Date:  1981-05-21     Completed Date:  1981-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  99-104     Citation Subset:  IM    
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MeSH Terms
Feeding Behavior / physiology*
Hypothalamus / physiology*
Macaca mulatta
Neurons / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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