Document Detail

Monitoring with the Somanetics INVOS 5100C after aneurysmal subarachnoid hemorrhage.
MedLine Citation:
PMID:  18360782     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Vasospasm is a major cause of morbidity after subarachnoid hemorrhage (SAH), and current screening techniques (angiography, transcranial Doppler [TCD], and clinical examination) have serious limitations. Brain oximetry is a promising noninvasive tool to detect reduced brain oxygenation from vasospasm. METHODS: Consecutive SAH patients at high risk for vasospasm were monitored with the INVOS (Somanetics, IL, USA) 5100C cerebral oximeter. We prospectively collected oximeter readings (rO2) with concurrent values for vital signs, intracerebral pressure (ICP), arterial blood gas measurement, and hemoglobin (HGB). Data were prospectively collected every 12 h and at clinical events (angiography, transfusion, etc.). We prospectively recorded clinical history, clinical events, radiology results, and outcomes. RESULTS: Six patients were measured 123 times. rO2 values were correlated with the contralateral side, HGB, blood pressure, and PaO2, but not with ICP or perfusion pressure. There were no measured effects of angiography or transfusion. Patterns relating rO2 readings to clinical, angiographic, or TCD evidence of vasospasm were unclear, and there were no associations with the outcome (cerebral infarction, NIH Stroke Scale, or modified Rankin Scale). CONCLUSION: INVOS rO2 readings are associated with other factors that relate to cerebral oxygen delivery but seem to be of limited use as a screening tool for vasospasm or cerebral infarction after SAH.
Andrew M Naidech; Bernard R Bendok; Michael L Ault; Thomas P Bleck
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Neurocritical care     Volume:  9     ISSN:  1541-6933     ISO Abbreviation:  Neurocrit Care     Publication Date:  2008  
Date Detail:
Created Date:  2008-10-31     Completed Date:  2009-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156086     Medline TA:  Neurocrit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  326-31     Citation Subset:  IM    
Northwestern University, Chicago, IL, USA.
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MeSH Terms
Aged, 80 and over
Aneurysm, Ruptured / complications,  metabolism*,  therapy
Brain / metabolism
Cerebral Infarction / etiology
Cohort Studies
Intracranial Aneurysm / complications,  metabolism*,  therapy
Middle Aged
Oximetry / instrumentation*
Oxyhemoglobins / metabolism
Point-of-Care Systems
Subarachnoid Hemorrhage / complications*,  metabolism*,  therapy
Vasospasm, Intracranial / diagnosis*,  etiology,  metabolism
Reg. No./Substance:

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