| Monitoring pulmonary function during exercise in children with asthma. | |
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MedLine Citation:
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PMID: 21460404 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective Exercise-induced bronchoconstriction (EIB) is defined as acute, reversible bronchoconstriction induced by physical exercise. It is widely believed that EIB occurs after exercise. However, in children with asthma the time to maximal bronchoconstriction after exercise is short, suggesting that the onset of EIB in such children occurs during exercise. Aim In this study the authors investigate pulmonary function during exercise in cold air in children with asthma. Methods 33 Children with asthma with a mean age of 12.3 years and a clinical history of exercise induced symptoms, underwent a prolonged, submaximal, exercise test of 12 min duration at approximately 80% of the predicted maximum heart rate. Pulmonary function was measured before and each minute during exercise. If EIB occurred (fall in forced expiratory volume in 1 s >15% from baseline), exercise was terminated and salbutamol was administered. Results 19 Children showed EIB. In 12 of these children bronchoconstriction occurred during exercise (breakthrough EIB), while seven children showed bronchoconstriction immediately after exercise (non-breakthrough EIB). Breakthrough EIB occurred between 6 and 10 min of exercise (mean 7.75 min). Conclusion In the majority of children with EIB in this study (ie, 12 out of 19), bronchoconstriction started during, and not after, a submaximal exercise test. |
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Authors:
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Janneke C van Leeuwen; Jean M M Driessen; Frans H C de Jongh; Wim M C van Aalderen; Boony J Thio |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-3 |
Journal Detail:
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Title: Archives of disease in childhood Volume: - ISSN: 1468-2044 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372434 Medline TA: Arch Dis Child Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pediatrics, Medisch Spectrum Twente, Enschede, The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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