Document Detail

Monitoring of patients with carcinoma of the large intestine by use of acute phase proteins and carcinoembryonic antigen.
MedLine Citation:
PMID:  6857457     Owner:  NLM     Status:  MEDLINE    
Fifty-two patients with resectable carcinoma of the colon and rectum have been monitored by three monthly serial estimations of three APRP (serum protein hexose, transferrin and ceruloplasmin) together with CEA. In 36 patients, subsequent clinical evidence of a recurrence of the disease developed during the study period. Monitoring with APRP can detect a recurrence of the disease at the subclinical stage in the majority of patients and appears to be complimentary to monitoring with CEA. However, due to the low incidence of surgical removal of recurrent carcinoma, this does not give real benefit for patients.
B N Gray; C Walker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery, gynecology & obstetrics     Volume:  156     ISSN:  0039-6087     ISO Abbreviation:  Surg Gynecol Obstet     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0101370     Medline TA:  Surg Gynecol Obstet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  777-80     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Adenocarcinoma / blood,  surgery
C-Reactive Protein / analysis*
Carcinoembryonic Antigen / analysis*
Ceruloplasmin / analysis*
Intestinal Neoplasms / blood*,  surgery
Intestine, Large / surgery
Neoplasm Recurrence, Local / diagnosis,  surgery
Postoperative Period
Transferrin / analysis*
Reg. No./Substance:
0/Carcinoembryonic Antigen; 11096-37-0/Transferrin; 9007-41-4/C-Reactive Protein; EC

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