| Monitoring microvascular free flaps with tissue oxygen measurement and PET. | |
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MedLine Citation:
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PMID: 18231800 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tissue oxygen measurement and positron emission tomography (PET) were evaluated as methods for predicting ischemia in microvascular free flaps of the head and neck. Ten patients with head and neck squamous cell cancer underwent resection of the tumour followed by microvascular reconstruction with a free flap. Tissue oxygenation of the flap (P(ti)O(2)) was continuously monitored for three postoperative (POP) days and the blood flow of the flap was assessed using oxygen-15 labelled water and PET. In three free flaps a perfusion problem was suspected due to a remarkable drop in P(ti)O(2)-values, due to two anastomosis problems and due to POP turgor. No flap losses occurred. During the blood flow measurements with PET [mean 8.5 mL 100 g(-1) min(-1 )(SD 2.5)], the mean P(ti)O(2) of the flaps [46.8 mmHg (SD 17.0)] appeared to correlate with each other in each patient (p<0.05, n=10). Tissue oxygenation measurement is a feasible monitoring system of free flaps. The perfusion-study with PET correlates with P(ti)O(2)-measurement. |
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Authors:
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Aleksi R Schrey; Ilpo A J Kinnunen; Reidar A Grénman; Heikki R I Minn; Kalle M J Aitasalo |
Publication Detail:
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Type: Journal Article Date: 2008-01-30 |
Journal Detail:
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Title: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery Volume: 265 Suppl 1 ISSN: 0937-4477 ISO Abbreviation: Eur Arch Otorhinolaryngol Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-18 Completed Date: 2009-01-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9002937 Medline TA: Eur Arch Otorhinolaryngol Country: Germany |
Other Details:
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Languages: eng Pagination: S105-13 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology-Head and Neck Surgery, Turku University Central Hospital, 20521 Turku, Finland. aleksi.schrey@tyks.fi |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carcinoma, Squamous Cell / surgery* Female Head and Neck Neoplasms / surgery* Humans Male Microsurgery Middle Aged Oxygen / analysis* Positron-Emission Tomography* Postoperative Care Prospective Studies Regional Blood Flow Surgical Flaps / blood supply* |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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