Document Detail

Monitoring in non-traumatic coma. Part I: Invasive intracranial measurements.
MedLine Citation:
PMID:  3415323     Owner:  NLM     Status:  MEDLINE    
The arterial blood pressure, intracranial pressure, and organ system failure scores were reviewed for 49 infants and children with non-traumatic coma from various causes. The neurological outcome was good in 21 patients, moderate in five, and poor in 23. There was no significant difference in maximum intracranial pressures between patients with a good outcome and those with a poor one, but patients with a poor outcome had significantly lower minimum cerebral perfusion pressures. During the period of admission 18 patients had cardiovascular failure, none had renal failure, and two developed severe coagulopathy. Seventeen of the 19 patients in whom at least one of these systems failed died. Our findings emphasise the diversity of illnesses associated with raised intracranial pressure in children and the number who develop multiple organ failure, and the values and limitations of using minimum cerebral perfusion pressure and the organ system failure scores as guides to severity of illness and prognosis.
R C Tasker; D J Matthew; P Helms; R Dinwiddie; S Boyd
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  63     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-10-07     Completed Date:  1988-10-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  888-94     Citation Subset:  AIM; IM    
Hospital for Sick Children, London.
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MeSH Terms
Acute Disease
Blood Pressure
Cerebral Arteries / physiopathology*
Cerebrovascular Circulation*
Child, Preschool
Coma / etiology,  physiopathology*
Infant, Newborn
Intracranial Pressure*
Monitoring, Physiologic / methods
Retrospective Studies

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