Document Detail

Monitoring of blood coagulation in open heart surgery. I. Effects of conventional dosages of heparin and protamine.
MedLine Citation:
PMID:  7468137     Owner:  NLM     Status:  MEDLINE    
In twenty unselected patients coming for surgery with cardio-pulmonary by-pass coagulation studies were performed. Laboratory results before and after by-pass were compared with serial measurements of ACtivated Clotting Times (ACT) during and after operation using conventional dosages of heparin and protamine. Values of ACT's are presented and compared with a previously published protocol according to Bull (1). Monitoring of ACT during operation was found to be easily applicable and highly desirable. Overdosage of both heparin and protamine was suggested as a correctable cause of proven abnormal coagulation after cardio-pulmonary by-pass.
S J Dercksen; G H Linssen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  31     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  1980  
Date Detail:
Created Date:  1981-04-13     Completed Date:  1981-04-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  113-9     Citation Subset:  IM    
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MeSH Terms
Blood Coagulation / drug effects*
Cardiac Surgical Procedures*
Cardiopulmonary Bypass
Child, Preschool
Heparin / administration & dosage*
Intraoperative Care*
Middle Aged
Monitoring, Physiologic
Protamines / administration & dosage*
Whole Blood Coagulation Time
Reg. No./Substance:
0/Protamines; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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