| Monitoring the activity of tyrosinase on a tyramine/dopamine-functionalized surface by force microscopy. | |
| | |
MedLine Citation:
|
PMID: 17567175 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Tyrosinase activity is monitored by pi-donor-acceptor force interactions between a bipyridinium-modified AFM tip and the biocatalytic reaction product generated on a tyramine- (or dopamine-) modified surface. Upon oxidation of the surface to dopaquinone as a result of tyrosinase activity, force interactions are switched "OFF". After reduction of the resulting surface with ascorbic acid, forces are quantitatively reestablished as a result of the formation of the dopamine-functionalized surfaces. The method provides a general approach to design biosensors using force interactions as the readout signal. |
| | |
Authors:
|
Adam B Braunschweig; Roey Elnathan; Itamar Willner |
Related Documents
:
|
15837495 - The dynamics of impacting water droplets on alkanethiol self-assembled monolayers with ... 21195045 - Acanthamoeba t3, t4 and t5 in swimming-pool waters from southern brazil. 19154045 - Understanding rubber friction in the presence of water using sum-frequency generation s... 16460085 - Nanoengineered multiscale hierarchical structures with tailored wetting properties. 22125255 - Activation of batao(2) n photocatalyst for enhanced non-sacrificial hydrogen evolution ... 16363485 - Bisphenol a analog-imprinted polymers prepared by an immobilized template on a modified... |
Publication Detail:
|
Type: Journal Article; Review Date: 2007-06-14 |
Journal Detail:
|
Title: Nano letters Volume: 7 ISSN: 1530-6984 ISO Abbreviation: Nano Lett. Publication Date: 2007 Jul |
Date Detail:
|
Created Date: 2007-07-11 Completed Date: 2007-08-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101088070 Medline TA: Nano Lett Country: United States |
Other Details:
|
Languages: eng Pagination: 2030-6 Citation Subset: IM |
Affiliation:
|
Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biosensing Techniques
/
instrumentation Dopamine* / chemistry, metabolism Microscopy, Atomic Force* Monophenol Monooxygenase / analysis*, chemistry, physiology Nanotechnology Tyramine* / chemistry, metabolism |
| Chemical | |
Reg. No./Substance:
|
51-67-2/Tyramine; EC 1.14.18.1/Monophenol Monooxygenase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: 3D electron microscopy study of metal particles inside multiwalled carbon nanotubes.
Next Document: Gate-defined quantum dots in intrinsic silicon.