Document Detail


Monitoring CD4 in whole blood with an opto-fluidic detector based on spatially modulated fluorescence emission.
MedLine Citation:
PMID:  21432992     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We describe a new optical detection technique, termed "spatially modulated fluorescence emission," that delivers high signal-to-noise discrimination without precision optics to enable a flow cytometer that can combine high performance, robustness, compactness, low cost, and ease of use. The detection technique is demonstrated with measurements of absolute CD4+ and percentage CD4 counts in human blood. Benchmarking against a commonly used commercial instrument for this test yields excellent agreement for both absolute CD4 and percentage CD4. © 2011 International Society for Advancement of Cytometry.
Authors:
Peter Kiesel; Markus Beck; Noble Johnson
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytometry. Part A : the journal of the International Society for Analytical Cytology     Volume:  79     ISSN:  1552-4930     ISO Abbreviation:  Cytometry A     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235694     Medline TA:  Cytometry A     Country:  United States    
Other Details:
Languages:  eng     Pagination:  317-24     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 International Society for Advancement of Cytometry.
Affiliation:
Palo Alto Research Center, Electronic Materials and Devices Laboratory, Palo Alto, CA 94304. peter.kiesel@parc.com.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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