| Monitored anesthetic care for outpatient cataract surgery with alfentanil. | |
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MedLine Citation:
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PMID: 2285718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Alfentanil, a short-acting congener of fentanyl, was studied as an analgesic sedative in monitored anesthetic care for outpatient cataract surgery with the intent of investigating efficacy in this setting and establishing dosage guidelines. Nineteen outpatients were studied, all of whom received droperidol 0.625 mg and midazolam 0.5 to 1.0 mg prior to a bolus dose of alfentanil preceding the administration of local anesthetic facial nerve and retrobulbar blocks. Alfentanil was titrated to achieve patient comfort during block administration, and sedatives were repeated as necessary intraoperatively. A mean alfentanil dose of 8.9 micrograms/kg was found to be effective. Eighteen patients (94%) rated the discomfort of local anesthetic blocks as absent or mild, and only 1 patient (5%) rated the blocks as severely painful. No severe cardiorespiratory or central nervous system side effects were observed, and 15% of patients were nauseated postoperatively despite droperidol administration. It can be concluded that alfentanil is an effective sedative in outpatient cataract surgery with minimal side effects reported in this clinical study. |
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Authors:
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C A Griffis |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Nurse anesthesia Volume: 1 ISSN: 0897-7437 ISO Abbreviation: Nurse Anesth Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1991-03-28 Completed Date: 1991-03-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9009407 Medline TA: Nurse Anesth Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 71-8 Citation Subset: N |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Alfentanil / administration & dosage, pharmacokinetics, therapeutic use* Ambulatory Care* Cataract Extraction* Humans Injections, Intravenous Middle Aged Monitoring, Physiologic Nerve Block |
| Chemical | |
Reg. No./Substance:
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71195-58-9/Alfentanil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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