| Molluscicides in schistosomiasis control. | |
| | |
MedLine Citation:
|
PMID: 6975179 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although mollusciciding can be a cost-effective method of controlling schistosomiasis transmission, only one organic molluscicide, niclosamide, is now being produced commercially, and only a few compounds are at present being tested in the laboratory. In future, improved cost-effective use of molluscicides will require more precise knowledge of schistosomiasis transmission patterns in each endemic area and improved application techniques. In snail control studies using controlled-release formulations only the organotins, especially tributyltin oxide (TBTO), have given satisfactory long-term results. However, large-scale field trials of organotin formulations have not been implemented and their use cannot be recommended as their chronic toxicity in mammals has not yet been determined. The development of molluscicides of indigenous plant origin deserves support. Endod, derived from the berries of the climbing plant Phytolacca dodecandra, is the most extensively tested plant molluscicide, but data on its chronic toxicity to non-target organisms are lacking. The mode of action of molluscicides has not been extensively studied, though knowledge of the properties required of molluscicidal molecules has contributed to the discovery and development of niclosamide and nicotinanilide. In general, molluscicides probably cause stress on the water balance system, which in gastropods in thought to be under neurosecretory control. |
| | |
Authors:
|
F S McCullough; P Gayral; J Duncan; J D Christie |
Related Documents
:
|
2603919 - Lymph flow rate response to angiotensin ii is decreased in pregnant sheep. 3899499 - Adaptations of adipose tissue metabolism and number of insulin receptors in pregnant sh... 968949 - Haematological values of nigerian goats and sheep. 8606939 - Interferon, the oxytocin receptor and the maternal recognition of pregnancy in ruminant... 7988159 - Cardiac rhythm disturbances due to caval occlusion during hepatic cryosurgery. 8764239 - Endothelial vasodilator production by uterine and systemic arteries. i. effects of ang ... 15826689 - Production of piglets with sexed semen employing a non-surgical insemination technique. 127839 - Genetic and endocrine studies of the pregnancy-blocking pheromone of mice. 8678449 - Problematic renal calculi presenting during pregnancy. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Bulletin of the World Health Organization Volume: 58 ISSN: 0042-9686 ISO Abbreviation: Bull. World Health Organ. Publication Date: 1980 |
Date Detail:
|
Created Date: 1982-01-20 Completed Date: 1982-01-20 Revised Date: 2010-10-26 |
Medline Journal Info:
|
Nlm Unique ID: 7507052 Medline TA: Bull World Health Organ Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 681-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Drug Resistance Humans Molluscacides / administration & dosage, therapeutic use* Niclosamide / therapeutic use Plants, Medicinal Schistosomiasis / drug therapy, prevention & control* Trialkyltin Compounds / therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Molluscacides; 0/Trialkyltin Compounds; 50-65-7/Niclosamide; 56-35-9/bis(tri-n-butyltin)oxide |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Immunological recognition and effector mechanisms in infectious diseases.
Next Document: Microbiological surveillance of intra-neighbourhood E1 Tor cholera transmission in rural Bangladesh.