Document Detail

"Molecular trinity" for soft nanomaterials: Integrating nucleobases, amino acids, and glycosides to construct multifunctional hydrogelators.
MedLine Citation:
PMID:  24368929     Owner:  NLM     Status:  Publisher    
This highlight introduces the development of hydrogelators consisting of nucleobases, amino acids, and glycosides (i.e., molecular trinity), or nucleobases and amino acids (i.e., nucleopeptides). These novel small molecule hydrogelators self-assemble in water to form stable supramolecular nanofibers/hydrogels and exhibit useful biological properties (e.g., biocompatibility, biostability, and the ability to bind and transport DNA into live cells). The approach discussed here not only provides a new strategy to develop soft biomaterials as a form of nanomedicines, but also contributes to the understanding of molecular self-assembly in water by modulating the non-covalent interactions derived from the three basic building blocks used in living organisms.
Xinming Li; Yi Kuang; Bing Xu
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Publication Detail:
Journal Detail:
Title:  Soft matter     Volume:  8     ISSN:  1744-683X     ISO Abbreviation:  Soft Matter     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2013-12-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101295070     Medline TA:  Soft Matter     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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