Document Detail

Molecular targeted therapies for renal cell carcinoma.
MedLine Citation:
PMID:  18163945     Owner:  NLM     Status:  MEDLINE    
New advances in technology to directly target specific molecular events in the proliferation of cancer have led to promising results in renal cell carcinoma. Response rates in excess of 70% and complete responses in advanced (metastatic) renal cell carcinoma have caused a change in the paradigm of treatment from immunotherapy. Toxicities are significant, but manageable and pushing the toxicity to tolerability may increase the response rate.
Sam D Graham; Mary Elizabeth Warden; Jeffrey Lou
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Canadian journal of urology     Volume:  14 Suppl 1     ISSN:  1195-9479     ISO Abbreviation:  Can J Urol     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-31     Completed Date:  2008-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515842     Medline TA:  Can J Urol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  48-52     Citation Subset:  IM    
Urologic Specialists of Virginia, Richmond, VA 23225, USA.
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MeSH Terms
Antineoplastic Agents / therapeutic use*
Carcinoma, Renal Cell / drug therapy*
Immunotherapy / methods*
Kidney Neoplasms / drug therapy*
Treatment Outcome
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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