Document Detail


Molecular targeted therapies for renal cell carcinoma.
MedLine Citation:
PMID:  18163945     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
New advances in technology to directly target specific molecular events in the proliferation of cancer have led to promising results in renal cell carcinoma. Response rates in excess of 70% and complete responses in advanced (metastatic) renal cell carcinoma have caused a change in the paradigm of treatment from immunotherapy. Toxicities are significant, but manageable and pushing the toxicity to tolerability may increase the response rate.
Authors:
Sam D Graham; Mary Elizabeth Warden; Jeffrey Lou
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Canadian journal of urology     Volume:  14 Suppl 1     ISSN:  1195-9479     ISO Abbreviation:  Can J Urol     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-31     Completed Date:  2008-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515842     Medline TA:  Can J Urol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  48-52     Citation Subset:  IM    
Affiliation:
Urologic Specialists of Virginia, Richmond, VA 23225, USA.
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / therapeutic use*
Carcinoma, Renal Cell / drug therapy*
Humans
Immunotherapy / methods*
Kidney Neoplasms / drug therapy*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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