| Molecular pathogenesis and prevention of prostate cancer. | |
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MedLine Citation:
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PMID: 15160993 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies in laboratory animals indicate inhibition of chemically-induced carcinoma by cystine-rich diets enhancing the cysteine-GSH antioxidant system. The progression of carcinoma of the prostate is also inhibited by these diets, which were later found to raise the level of GSH in the prostate epithelium of man. New data presented at the July 13, 2003 meeting of the American Association for Cancer Research indicates that higher levels of total cysteine in plasma may predict a reduced risk for breast cancer. This prospective investigation was conducted among 32,000 women in the Nurses Health study. The previously reported prostate cancer data appears then not to be strictly gender-related as the antioxidant role of the cysteine-GSH system may also apply to breast cancer prevention. |
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Authors:
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Gustavo Bounous; Dieter Beer |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Anticancer research Volume: 24 ISSN: 0250-7005 ISO Abbreviation: Anticancer Res. Publication Date: 2004 Mar-Apr |
Date Detail:
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Created Date: 2004-05-26 Completed Date: 2004-07-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8102988 Medline TA: Anticancer Res Country: Greece |
Other Details:
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Languages: eng Pagination: 553-4 Citation Subset: IM |
Affiliation:
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Research and Development Department, Immunotec Research Ltd., Vaudreuil-Dorion, Quebec, Canada. jmolson@immunotec.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cysteine / metabolism* Diet Glutathione / metabolism* Humans Male Oxidation-Reduction Prostatic Neoplasms / metabolism*, prevention & control* |
| Chemical | |
Reg. No./Substance:
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52-90-4/Cysteine; 70-18-8/Glutathione |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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