Document Detail

Molecular oscillation behind the clockface.
MedLine Citation:
PMID:  14769863     Owner:  NLM     Status:  MEDLINE    
The earth rotates on its own axis while orbiting around the sun. This regular movement of the solar system results in cyclic changes of the light condition of the earth with a period of 24 h, although the lengths of daytime and nighttime depend on the latitude. The organisms living on the earth have evolved an internal time-measuring system called the "circadian clock," which ticks with a period of approximately 24 h in order to adapt to the environment and to anticipate the next cycle. The fact that most of existing organisms retain the circadian clock suggests that the clock-ownership must have been advantageous over non-ownership during their evolution. Here I will introduce the background of the research field of circadian rhythm and present an outline of this Special Review series, which is composed of three articles that review recent research into the molecular mechanisms of the three types of circadian clock systems in vertebrates.
Yoshitaka Fukada
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of biochemistry     Volume:  134     ISSN:  0021-924X     ISO Abbreviation:  J. Biochem.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2004-02-10     Completed Date:  2004-10-21     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0376600     Medline TA:  J Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  773-5     Citation Subset:  IM    
Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033.
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MeSH Terms
Biological Clocks / genetics,  physiology*
Circadian Rhythm / genetics,  physiology*
Feedback, Physiological / genetics,  physiology

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