| Molecular mechanisms of renin release. | |
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MedLine Citation:
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PMID: 1705619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Renin secretion from renal juxtaglomerular cells is controlled by the intrarenal blood pressure, sodium chloride load of the organism, sympathetic nerve activity, and a number of hormones. The mechanisms by which these parameters exert their effects are not well understood. However, it is reasonable to assume that they act via signal transduction systems, implying the role of second messenger molecules in the control of renin secretion. This article summarizes present knowledge about the cellular mechanisms of renin secretion. Moreover, current concepts about the mechanisms by which the blood pressure and the sodium chloride load could influence renin secretion are discussed. |
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Authors:
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A Kurtz; H Scholz; R della Bruna |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of cardiovascular pharmacology Volume: 16 Suppl 4 ISSN: 0160-2446 ISO Abbreviation: J. Cardiovasc. Pharmacol. Publication Date: 1990 |
Date Detail:
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Created Date: 1991-04-08 Completed Date: 1991-04-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902492 Medline TA: J Cardiovasc Pharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S1-7 Citation Subset: IM |
Affiliation:
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Physiologisches Institut der Universität Zürich, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiotensin II
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physiology Blood Pressure / drug effects Calcium / physiology Humans Juxtaglomerular Apparatus / anatomy & histology, drug effects, physiology* Renin / secretion* Sodium Chloride / pharmacology |
| Chemical | |
Reg. No./Substance:
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11128-99-7/Angiotensin II; 7440-70-2/Calcium; 7647-14-5/Sodium Chloride; EC 3.4.23.15/Renin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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