| Molecular mechanisms for plasmacytoid dendritic cell function and development. | |
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MedLine Citation:
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PMID: 20849871 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Dendritic cells (DCs) are activated by immune adjuvants in a DC subset-specific manner. Plasmacytoid DC (pDC) is a unique subset that senses nucleic acid immune adjuvants only through two Toll-like receptors (TLRs), TLR7 and TLR9 and produces large amounts of type I interferons. Here I review recent trend in pDC function and development. |
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Authors:
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Tsuneyasu Kaisho |
Publication Detail:
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Type: Journal Article Date: 2010-09-17 |
Journal Detail:
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Title: Vaccine Volume: 28 ISSN: 1873-2518 ISO Abbreviation: Vaccine Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406899 Medline TA: Vaccine Country: Netherlands |
Other Details:
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Languages: eng Pagination: 8046-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Laboratory for Host Defense, RIKEN Research Center for Allergy and Immunology, Suehiro-cho 1-7-22, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan. tkaisho@rcai.riken.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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