Document Detail


Molecular mechanisms of developmental timing in C. elegans and Drosophila.
MedLine Citation:
PMID:  11703937     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Characterization of the heterochronic genes has provided a strong foundation for understanding the molecular mechanisms of developmental timing in C. elegans. In apparent contrast, studies of developmental timing in Drosophila have demonstrated a central role for gene cascades triggered by the steroid hormone ecdysone. In this review, I survey the molecular mechanisms of developmental timing in C. elegans and Drosophila and outline how common regulatory pathways are beginning to emerge.
Authors:
C S Thummel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Developmental cell     Volume:  1     ISSN:  1534-5807     ISO Abbreviation:  Dev. Cell     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-11-14     Completed Date:  2001-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101120028     Medline TA:  Dev Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  453-65     Citation Subset:  IM    
Affiliation:
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah, Salt Lake City 84112, USA. carl.thummel@genetics.utah.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Caenorhabditis elegans / embryology*,  genetics*
Caenorhabditis elegans Proteins / genetics
Drosophila / embryology*,  genetics*
Drosophila Proteins / genetics
Gene Expression Regulation, Developmental / physiology*
Chemical
Reg. No./Substance:
0/Caenorhabditis elegans Proteins; 0/Drosophila Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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