Document Detail


Molecular imprinting made easy.
MedLine Citation:
PMID:  15212530     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A simple method of molecular imprinting is presented that uses a single cross-linking monomer N,O-bismethacryloyl ethanolamine (NOBE) along with template, initiator, and solvent. This formulation eliminates the need for additional functional monomers and empirical optimization of relative ratios of functional monomers, cross-linkers, and template. In fact, utilization of NOBE alone often provides molecularly imprinted polymers (MIPs) with higher performance than MIPs incorporating functional monomer (e.g., methacrylic acid).
Authors:
Martha Sibrian-Vazquez; David A Spivak
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  126     ISSN:  0002-7863     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-23     Completed Date:  2004-09-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7827-33     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
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MeSH Terms
Descriptor/Qualifier:
Binding Sites
Chromatography, High Pressure Liquid
Cross-Linking Reagents / chemistry*
Ethanolamine / chemistry
Methacrylates / chemistry
Molecular Structure
Naphthols / chemistry
Polymers / chemistry*
Solvents / chemistry
Chemical
Reg. No./Substance:
0/Cross-Linking Reagents; 0/Methacrylates; 0/Naphthols; 0/Polymers; 0/Solvents; 135-19-3/2-naphthol; 141-43-5/Ethanolamine; 79-41-4/methacrylic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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