| Molecular imaging with targeted contrast ultrasound. | |
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MedLine Citation:
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PMID: 19372662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Molecular imaging with contrast-enhanced ultrasound uses targeted microbubbles that are retained in diseased tissue. The resonant properties of these microbubbles produce acoustic signals in an ultrasound field. The microbubbles are targeted to diseased tissue by using certain chemical constituents in the microbubble shell or by attaching disease-specific ligands such as antibodies to the microbubble. In this review, we discuss the applications of this technique to pathological states in the cerebrovascular system including atherosclerosis, tumor angiogenesis, ischemia, intravascular thrombus, and inflammation. |
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Authors:
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Mark Piedra; Achim Allroggen; Jonathan R Lindner |
Publication Detail:
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Type: Journal Article; Review Date: 2009-04-16 |
Journal Detail:
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Title: Cerebrovascular diseases (Basel, Switzerland) Volume: 27 Suppl 2 ISSN: 1421-9786 ISO Abbreviation: Cerebrovasc. Dis. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-04-17 Completed Date: 2009-07-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9100851 Medline TA: Cerebrovasc Dis Country: Switzerland |
Other Details:
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Languages: eng Pagination: 66-74 Citation Subset: IM |
Copyright Information:
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Copyright 2009 S. Karger AG, Basel. |
Affiliation:
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Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR 97239, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media* Humans Inflammation / ultrasonography Intracranial Arteriosclerosis / ultrasonography Microbubbles* Neovascularization, Pathologic / ultrasonography Thrombosis / ultrasonography Ultrasonography, Interventional / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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