Document Detail


Molecular imaging of cell-based cancer immunotherapy.
MedLine Citation:
PMID:  21308113     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cell-based cancer immunotherapy represents a new and powerful weapon in the arsenal of anticancer treatments. Non-invasive monitoring of the disposition, migration and destination of therapeutic cells will facilitate the development of cell based therapy. The therapeutic cells can be modified intrinsically by a reporter gene or labeled extrinsically by introducing imaging probes into the cells or on the cell surface before transplant. Various advanced non-invasive molecular imaging techniques are playing important roles in optimizing cellular therapy by tracking cells and monitoring the therapeutic effects of transplanted cells in vivo. This review will summarize the application of multiple molecular imaging modalities in cell-based cancer immunotherapy.
Authors:
Gang Liu; Magdalena Swierczewska; Gang Niu; Xiaoming Zhang; Xiaoyuan Chen
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2011-02-09
Journal Detail:
Title:  Molecular bioSystems     Volume:  7     ISSN:  1742-2051     ISO Abbreviation:  Mol Biosyst     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-15     Completed Date:  2011-07-05     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  101251620     Medline TA:  Mol Biosyst     Country:  England    
Other Details:
Languages:  eng     Pagination:  993-1003     Citation Subset:  IM    
Affiliation:
Sichuan Key Laboratory of Medical Imaging, Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong 637007, China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Humans
Immunotherapy*
Magnetic Resonance Imaging
Molecular Imaging*
Neoplasms / therapy*
Radionuclide Imaging
Grant Support
ID/Acronym/Agency:
Z99 EB999999/EB/NIBIB NIH HHS; ZIA EB000073-01/EB/NIBIB NIH HHS
Comments/Corrections

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