| Molecular imaging of cell-based cancer immunotherapy. | |
MedLine Citation:
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PMID: 21308113 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cell-based cancer immunotherapy represents a new and powerful weapon in the arsenal of anticancer treatments. Non-invasive monitoring of the disposition, migration and destination of therapeutic cells will facilitate the development of cell based therapy. The therapeutic cells can be modified intrinsically by a reporter gene or labeled extrinsically by introducing imaging probes into the cells or on the cell surface before transplant. Various advanced non-invasive molecular imaging techniques are playing important roles in optimizing cellular therapy by tracking cells and monitoring the therapeutic effects of transplanted cells in vivo. This review will summarize the application of multiple molecular imaging modalities in cell-based cancer immunotherapy. |
Authors:
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Gang Liu; Magdalena Swierczewska; Gang Niu; Xiaoming Zhang; Xiaoyuan Chen |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2011-02-09 |
Journal Detail:
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Title: Molecular bioSystems Volume: 7 ISSN: 1742-2051 ISO Abbreviation: Mol Biosyst Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-15 Completed Date: 2011-07-05 Revised Date: 2013-06-30 |
Medline Journal Info:
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Nlm Unique ID: 101251620 Medline TA: Mol Biosyst Country: England |
Other Details:
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Languages: eng Pagination: 993-1003 Citation Subset: IM |
Affiliation:
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Sichuan Key Laboratory of Medical Imaging, Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong 637007, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Humans Immunotherapy* Magnetic Resonance Imaging Molecular Imaging* Neoplasms / therapy* Radionuclide Imaging |
| Grant Support | |
ID/Acronym/Agency:
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Z99 EB999999/EB/NIBIB NIH HHS; ZIA EB000073-01/EB/NIBIB NIH HHS |
| Comments/Corrections | |
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