Document Detail


Molecular identification of Borrelia crocidurae in a patient returning from Senegal.
MedLine Citation:
PMID:  21691399     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Borrelia spp. are pathogens responsible for worldwide tickborne relapsing fever (TBRF). In West Africa, TBRF is due to a single species, Borrelia crocidurae, transmitted by the soft-body tick Ornithodoros sonrai. We report a case of B crocidurae infection in a French tourist in Senegal, diagnosed by molecular biology using 16S rDNA, flaB, and the 16S-23S intergenic spacer. We found six imported cases reported in travellers (since 1999). We review here clinical and molecular aspects and pathophysiology, and discuss diagnostic methods and therapeutic regimens. In the coming years, this emerging disease will be of concern to more and more travellers returning from disease-endemic regions. Thus, physicians must be aware of its presentation and diagnosis, since the spontaneous outcome can be severe, and a simple treatment is effective.
Authors:
Matthieu Million; Cécile Cazorla; Barbara Doudier; Bernard La Scola; Philippe Parola; Michel Drancourt; Philippe Brouqui
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Publication Detail:
Type:  Journal Article     Date:  2009-02-20
Journal Detail:
Title:  BMJ case reports     Volume:  2009     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2009  
Date Detail:
Created Date:  2011-06-21     Completed Date:  2011-07-14     Revised Date:  2013-04-02    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
Faculté de médecine, Unité des rickettsies-CNRS URMITE 6236, 27, Bd Jean Moulin, Marseille, 13385, France.
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Erratum In:
BMJ Case Rep. 2009;2009:bcr0620080298corr1

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