Document Detail


Molecular genetics of thyroid and parathyroid neoplasia.
MedLine Citation:
PMID:  7857233     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There have been several recent advances in the understanding of the process of carcinogenesis in the thyroid and parathyroid glands. The specific abnormal molecules are, in many instances, well understood. This review provides an overview of the molecules in the cell that regulate cell growth and proliferation and identifies the molecules that have been found to be abnormal (or mutant) in various types of thyroid and parathyroid neoplasia.
Authors:
B G Robinson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Australian and New Zealand journal of surgery     Volume:  65     ISSN:  0004-8682     ISO Abbreviation:  Aust N Z J Surg     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-03-14     Completed Date:  1995-03-14     Revised Date:  2012-06-04    
Medline Journal Info:
Nlm Unique ID:  0373115     Medline TA:  Aust N Z J Surg     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  77-9     Citation Subset:  IM    
Affiliation:
Department of Molecular Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
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MeSH Terms
Descriptor/Qualifier:
Cell Cycle / genetics
Cell Division
Cyclins / genetics
DNA, Neoplasm / genetics
Drosophila Proteins*
Gene Rearrangement*
Humans
Mutation
Parathyroid Neoplasms / genetics*,  pathology
Proto-Oncogene Proteins / genetics
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases / genetics
Receptors, Thyrotropin / genetics
Thyroid Neoplasms / genetics*,  pathology
Chemical
Reg. No./Substance:
0/Cyclins; 0/DNA, Neoplasm; 0/Drosophila Proteins; 0/Proto-Oncogene Proteins; 0/Receptors, Thyrotropin; EC 2.7.10.1/Proto-Oncogene Proteins c-ret; EC 2.7.10.1/Receptor Protein-Tyrosine Kinases; EC 2.7.10.1/Ret oncogene protein, Drosophila

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