| Molecular evidence for transplacental transmission of Theileria equi from carrier mares to their apparently healthy foals. | |
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MedLine Citation:
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PMID: 17601669 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The intra-erythrocytic parasite Theileria equi is one of two tick-transmitted causative agents of equine piroplasmosis. Piroplasms of T. equi can be transmitted across the equine placenta and once a horse is infected, it appears to remain a lifelong carrier, since anti-theilerial drugs suppress but do not eliminate the parasite. Carrier mares may transmit the organism to their offspring and this may result in abortion or neonatal piroplasmosis, but observations by some researchers suggest that foals may be born as carriers yet remain apparently healthy. Using a T. equi-specific oligonucleotide probe, we have determined that transplacental transmission occurs early in equine foetal development and that carrier mares may give birth to healthy carrier foals. Investigation of parasite levels and the effect of maternal colostrum on the newborn suggests that colostral T. equi antibody may act to suppress parasitaemia in the newborn, reducing the incidence of clinical neonatal piroplasmosis. |
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Authors:
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M T E P Allsopp; B D Lewis; B L Penzhorn |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-06-29 |
Journal Detail:
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Title: Veterinary parasitology Volume: 148 ISSN: 0304-4017 ISO Abbreviation: Vet. Parasitol. Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-08-06 Completed Date: 2007-10-11 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7602745 Medline TA: Vet Parasitol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 130-6 Citation Subset: IM |
Affiliation:
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Onderstepoort Veterinary Institute, Private Bag X5, Onderstepoort 0110, South Africa. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Veterinary
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parasitology Animals Animals, Newborn Colostrum / immunology Disease Reservoirs / veterinary Female Fetus / parasitology* Horse Diseases / immunology, parasitology, transmission* Horses Immunity, Maternally-Acquired* Infectious Disease Transmission, Vertical / veterinary* Placenta / parasitology Pregnancy Pregnancy Complications, Parasitic / parasitology, veterinary* Theileria Theileriasis / immunology, parasitology, transmission* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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