Document Detail


Molecular epidemiological study on prevalence of human papillomaviruses in patients with common warts in Beijing area.
MedLine Citation:
PMID:  19462689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the circulation, distribution, and genomic diversity of HPVs in common warts in Beijing area of China. METHODS: Forty eight patients with pathologically diagnosed common warts were screened for the presence of HPV with HPV type-specific PCR and direct sequencing analysis. The genomic diversity of HPVs prevalent in Chinese patients was analyzed based on LCR. RESULTS: Forty one (85.5%) samples were positive for HPV DNA, 13 (31.7%)--HPV-57, 12 (29.3%)--HPV-1a, 7 (17%)--HPV-27 and 5(12.2%)--HPV-2a. Four cases were infected with two different HPV types, two (4.9%) with HPV-1a and HPV-27, one (2.4%) with HPV-1 and HPV-57 and one (2.4%) with HPV-27 and HPV-57. In contrast to the prevalence of single strain of novel HPV-57 variant and HPV-1 prototype, two HPV-2 and three HPV-27 novel variants were found to circulate in Beijing. CONCLUSION: HPV-1, -2, -27 and -57 are predominantly prevalent in patients with common warts in Beijing.
Authors:
Yan-Jun Lei; Chen Gao; Chen Wang; Jun Han; Jian-Ming Chen; Guang-Cai Xiang; Qi Shi; Hui-Ying Jiang; Wei Zhou; Run An; Chen-Fang Dong; Yu-Kang Yuan; Xiao-Ping Dong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomedical and environmental sciences : BES     Volume:  22     ISSN:  0895-3988     ISO Abbreviation:  Biomed. Environ. Sci.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-05-25     Completed Date:  2009-07-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8909524     Medline TA:  Biomed Environ Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  55-61     Citation Subset:  IM    
Affiliation:
State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
China / epidemiology
DNA, Viral
Female
Genetic Variation
Humans
Male
Middle Aged
Papillomaviridae / classification,  genetics,  isolation & purification*
Phylogeny
Prevalence
Warts / epidemiology*,  virology
Chemical
Reg. No./Substance:
0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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