Document Detail

Molecular diagnostic approach to liver tissue as an ancillary tool for liver histopathology.
MedLine Citation:
PMID:  17051447     Owner:  NLM     Status:  MEDLINE    
Diagnostic liver histopathology is currently based on the microscopic assessment of morphological and immunohistochemical features in a biopsy. In other fields of diagnostic pathology, it has been shown that the diagnostic process can be improved by the incorporation of ancillary molecular techniques and this will most likely also occur in liver pathology in the future. This article gives an overview of several liver diseases for which the diagnosis could be improved by the addition of a molecular technique to the classical histopathologic working method. For each of these diseases, the most promising molecular techniques are discussed. It is very likely that ancillary molecular techniques will be applied in routine practice to improve diagnosis and prognostication of liver tumors in the foreseeable future.
Louis Libbrecht; Tania Roskams
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in liver disease     Volume:  26     ISSN:  0272-8087     ISO Abbreviation:  Semin. Liver Dis.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-19     Completed Date:  2007-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8110297     Medline TA:  Semin Liver Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  328-36     Citation Subset:  IM    
Liver Research Unit of the Laboratory of Morphology and Molecular Pathology and Department of Pathology, University Hospitals of Leuven, Leuven, Belgium.
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MeSH Terms
Liver / pathology*
Liver Diseases / diagnosis*
Liver Neoplasms / diagnosis
Molecular Diagnostic Techniques*
RNA, Viral / analysis
Reg. No./Substance:
0/RNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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