Document Detail


Molecular diagnosis of soft tissue neoplasia: clinical applications and recent advances.
MedLine Citation:
PMID:  25109831     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Sarcomas are rare and heterogeneous neoplasms of mesenchymal tissues with diverse morphologies and clinical behavior. In the last few years, the discovery of specific genetic aberrations in these tumors has allowed better classification and understanding of mechanisms driving their pathogenesis. While the majority of sarcomas are still treated by traditional modalities, molecular markers driving the pathogenesis have paved the way for more accurate diagnosis and opportunity to explore other therapeutic strategies. This review discusses the available molecular tools in sarcoma diagnostics and highlight some of the biological significance of the recent discoveries and their clinical applications.
Authors:
Meera Hameed
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-9
Journal Detail:
Title:  Expert review of molecular diagnostics     Volume:  -     ISSN:  1744-8352     ISO Abbreviation:  Expert Rev. Mol. Diagn.     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101120777     Medline TA:  Expert Rev Mol Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-17     Citation Subset:  -    
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