Document Detail

Molecular diagnosis of lobomycosis-like disease in a bottlenose dolphin in captivity.
MedLine Citation:
PMID:  21838615     Owner:  NLM     Status:  MEDLINE    
We report the diagnosis and molecular characterization of lobomycosis-like lesions in a captive bottlenose dolphin. The clinical picture and the absence of growth in conventional media resembled the features associated with Lacazia loboi. However sequencing of ribosomal DNA and further phylogenetic analyses showed a novel sequence more related to Paracoccidioides brasilensis than to L. loboi. Moreover, the morphology of the yeast cells differed from those L. loboi causing infections humans. These facts suggest that the dolphin lobomycosis-like lesions might have been be caused by different a different fungus clustered inside the order Onygenales. A successful treatment protocol based on topic and systemic terbinafine is also detailed.
Fernando Esperón; Daniel García-Párraga; Edwige Nina Bellière; José Manuel Sánchez-Vizcaíno
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-08-15
Journal Detail:
Title:  Medical mycology     Volume:  50     ISSN:  1460-2709     ISO Abbreviation:  Med. Mycol.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-12-16     Completed Date:  2012-04-04     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  9815835     Medline TA:  Med Mycol     Country:  England    
Other Details:
Languages:  eng     Pagination:  106-9     Citation Subset:  IM    
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MeSH Terms
Animals, Zoo*
Bottle-Nosed Dolphin*
DNA, Fungal / chemistry,  genetics
Lobomycosis / pathology,  veterinary
Molecular Sequence Data
Paracoccidioides / cytology,  genetics,  isolation & purification*
Paracoccidioidomycosis / diagnosis,  microbiology,  pathology,  veterinary*
Sequence Analysis, DNA
Reg. No./Substance:
0/DNA, Fungal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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