Document Detail


Molecular determinants of scouting behavior in honey bees.
MedLine Citation:
PMID:  22403390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Little is known about the molecular basis of differences in behavior among individuals. Here we report consistent novelty-seeking behavior, across different contexts, among honey bees in their tendency to scout for food sources and nest sites, and we reveal some of the molecular underpinnings of this behavior relative to foragers that do not scout. Food scouts showed extensive differences in brain gene expression relative to other foragers, including differences related to catecholamine, glutamate, and γ-aminobutyric acid signaling. Octopamine and glutamate treatments increased the likelihood of scouting, whereas dopamine antagonist treatment decreased it. These findings demonstrate intriguing similarities in human and insect novelty seeking and suggest that this trait, which presumably evolved independently in these two lineages, may be subserved by conserved molecular components.
Authors:
Zhengzheng S Liang; Trang Nguyen; Heather R Mattila; Sandra L Rodriguez-Zas; Thomas D Seeley; Gene E Robinson
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  335     ISSN:  1095-9203     ISO Abbreviation:  Science     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-09     Completed Date:  2012-09-13     Revised Date:  2013-08-15    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1225-8     Citation Subset:  IM    
Affiliation:
Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Appetitive Behavior*
Bees / genetics*,  physiology*
Behavior, Animal
Brain / metabolism
Catecholamines / metabolism
Dopamine Antagonists / pharmacology
Exploratory Behavior*
Female
Gene Expression Profiling
Gene Expression Regulation
Genes, Insect
Glutamic Acid / metabolism
Male
Membrane Transport Proteins / genetics,  metabolism
Nesting Behavior
Octopamine / pharmacology
Oligonucleotide Array Sequence Analysis
Receptors, Neurotransmitter / genetics
Signal Transduction / genetics
Sodium Glutamate / pharmacokinetics
Transcriptome
gamma-Aminobutyric Acid / metabolism
Grant Support
ID/Acronym/Agency:
1DP1OD006416/OD/NIH HHS; R21 DA027548/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
0/Catecholamines; 0/Dopamine Antagonists; 0/Membrane Transport Proteins; 0/Receptors, Neurotransmitter; 104-14-3/Octopamine; 142-47-2/Sodium Glutamate; 56-12-2/gamma-Aminobutyric Acid; 56-86-0/Glutamic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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