| Molecular cloning and sequencing of sulfated glycoprotein-2 cDNA from testis of mouse: implications of two different mRNAs of SGP-2. | |
| | |
MedLine Citation:
|
PMID: 8352774 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We cloned a mouse homolog of sulfated glycoprotein-2 (SGP-2) cDNA by screening a mouse testicular cDNA library and its nucleotide sequence was determined. The predicted amino acid sequence of the cDNA shares 93% identity with that of rat SGP-2. The nucleotide sequences of both cDNAs show extensive homology throughout the open reading frames and 3' untranslated regions. The 5' untranslated regions, however, share homology only up to 28 bp upstream from the start codons; the rest of sequences are quite different. DNA sequence homology search to mouse SGP-2 cDNA through the EMBL/GenBank database and a recent study on the genomic organization of rat TRPM-2 gene suggest a possibility that there are at least two different SGP-2 mRNAs as a result of alternative splicing and/or different promoter usage in mouse. |
| | |
Authors:
|
K H Lee; Y M Ji; H M Lim; S C Lee; K H You |
Related Documents
:
|
1350294 - Structure of the mouse il-10 gene and chromosomal localization of the mouse and human g... 20353814 - Prediction of polycomb target genes in mouse embryonic stem cells. 7492614 - Genomic and cdna cloning of a novel mouse lipoxygenase gene. 1730064 - Unique use of alternative polyadenylation signals in the mouse aldolase b gene. 17084644 - An improved molecular phylogeny of the nematoda with special emphasis on marine taxa. 11727824 - Protein-dna interaction and cpg methylation at rep*/vil-10p of latent epstein-barr viru... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Biochemical and biophysical research communications Volume: 194 ISSN: 0006-291X ISO Abbreviation: Biochem. Biophys. Res. Commun. Publication Date: 1993 Aug |
Date Detail:
|
Created Date: 1993-09-15 Completed Date: 1993-09-15 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0372516 Medline TA: Biochem Biophys Res Commun Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1175-80 Citation Subset: IM |
Affiliation:
|
Department of Biology, College of Natural Sciences, College of Pharmacy, Chungnam National University, Taejon, Korea. |
| Data Bank Information | |
Bank Name/Acc. No.:
|
GENBANK/D14017; D14077; S63834; S63835; S63836; S63837; S63838; S64544; U11085; U11086; U11087 |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alternative Splicing Amino Acid Sequence Animals Base Sequence Cloning, Molecular Clusterin Exons / genetics Gene Library Glycoproteins / genetics* Male Mice Molecular Chaperones* Molecular Sequence Data Promoter Regions, Genetic / genetics RNA, Messenger / genetics* Sequence Analysis, DNA Sequence Homology, Nucleic Acid Testis / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Clu protein, mouse; 0/Clusterin; 0/Glycoproteins; 0/Molecular Chaperones; 0/RNA, Messenger |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Glycoprotein 2 of zymogen granule membranes shares immunological cross-reactivity and sequence simil...
Next Document: Complement component C3-derived neutrophil chemotactic factors purified from exudate of rat carragee...