Document Detail

Molecular characterization of serotype G9 rotaviruses circulating in South Korea between 2005 and 2010.
MedLine Citation:
PMID:  23154880     Owner:  NLM     Status:  In-Data-Review    
A total of 18 rotavirus G9 strains in South Korea were collected during five rotavirus seasons between 2005 and 2010. The relationship between these strains was examined by analyzing the genetic variation of two major structural genes, VP7 and VP4. All the rotavirus isolates were of the G9P[8] genotype. The VP7 phylogenetic analysis demonstrated that all of the G9 rotaviruses circulating in South Korea belonged to lineage IIId and were within three single clusters. The amino acid comparison of the antigenic regions of the VP7 gene suggests possible common progenitors of these strains. Phylogenetic analysis of P[8] VP4 genotypes indicated three lineages, P[8]-2, P[8]-3, and P[8]-4, with P[8]-3 being the most common. The results of this study provide information on the genetic relatedness of rotavirus G9 strains circulating in South Korea over recent years and can be utilized for the development of effective vaccines and the identification of reference strains for future efficacy studies. J. Med. Virol. 85:171-178, 2012. © 2012 Wiley Periodicals, Inc.
Van Thai Than; Hyeonji Kang; Inseok Lim; Wonyong Kim
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical virology     Volume:  85     ISSN:  1096-9071     ISO Abbreviation:  J. Med. Virol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-11-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705876     Medline TA:  J Med Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Department of Microbiology, Chung-Ang University College of Medicine, Seoul, South Korea.
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