| Molecular characterization of interleukin 2. | |
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MedLine Citation:
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PMID: 6602719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The isolation of specific T cell growth factors termed interleukin 2 (IL 2) is changing the approach to understanding T cell function. This class of growth factors has allowed te establishment of a number of human and murine T cell lines. We summarize the biochemical properties of human and murine IL 2. Studies have been initiated to isolate mRNA encoding for IL 2. Such RNA can be translated in rabbit reticulocyte lysates yielding IL. 2. This RNA may be useful for the development of probes to isolate lymphokine genes. |
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Authors:
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J D Watson; D Y Mochizuki; S Gillis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Federation proceedings Volume: 42 ISSN: 0014-9446 ISO Abbreviation: Fed. Proc. Publication Date: 1983 Jul |
Date Detail:
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Created Date: 1983-08-11 Completed Date: 1983-08-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372771 Medline TA: Fed Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2747-52 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Glycosides / analysis Humans Interleukin-2 / genetics, isolation & purification* Kinetics Lymphocyte Activation Mice Protein Biosynthesis RNA, Messenger / genetics Rabbits Reticulocytes / metabolism Species Specificity Spleen / immunology T-Lymphocytes / immunology |
| Chemical | |
Reg. No./Substance:
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0/Glycosides; 0/Interleukin-2; 0/RNA, Messenger |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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