Document Detail

Molecular call and response: the physiology of bacterial small RNAs.
MedLine Citation:
PMID:  21843668     Owner:  NLM     Status:  MEDLINE    
The vital role of bacterial small RNAs (sRNAs) in cellular regulation is now well-established. Although many diverse mechanisms by which sRNAs bring about changes in gene expression have been thoroughly described, comparatively less is known about their biological roles and effects on cell physiology. Nevertheless, for some sRNAs, insight has been gained into the intricate regulatory interplay that is required to sense external environmental and internal metabolic cues and turn them into physiological outcomes. Here, we review examples of regulation by selected sRNAs, emphasizing signals and regulators required for sRNA expression, sRNA regulatory targets, and the resulting consequences for the cell. We highlight sRNAs involved in regulation of the processes of iron homeostasis (RyhB, PrrF, and FsrA) and carbon metabolism (Spot 42, CyaR, and SgrS).
Gregory R Richards; Carin K Vanderpool
Related Documents :
22009728 - Angiotensin ii signaling promotes follicle growth and dominance in cattle.
21613208 - Insulin growth factor-2 binding protein 3 (igf2bp3) is a glioblastoma-specific marker t...
9182958 - Reelin mrna expression during mouse brain development.
21716668 - Protein expression of mesenchymal stem cells after transfection of pcdna3.1⁻-hvegf₁...
25035988 - Hyperoxia reverses glucotoxicity-induced inhibition of insulin secretion in rat ins-1 ...
9891068 - Cyclin d1 expression mediated by phosphatidylinositol 3-kinase through mtor-p70(s6k)-in...
Publication Detail:
Type:  Journal Article; Review     Date:  2011-08-06
Journal Detail:
Title:  Biochimica et biophysica acta     Volume:  1809     ISSN:  0006-3002     ISO Abbreviation:  Biochim. Biophys. Acta     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-04     Completed Date:  2011-11-23     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  0217513     Medline TA:  Biochim Biophys Acta     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  525-31     Citation Subset:  IM    
Copyright Information:
2011 Elsevier B.V. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Carbon / chemistry
Cyclic AMP / metabolism
Escherichia coli / genetics
Gene Expression Regulation, Bacterial
Genes, Bacterial
Iron / metabolism
Models, Biological
Models, Genetic
RNA, Bacterial / genetics*,  physiology*
RNA, Untranslated / genetics
Grant Support
Reg. No./Substance:
0/RNA, Bacterial; 0/RNA, Untranslated; 7440-44-0/Carbon; E0399OZS9N/Cyclic AMP; E1UOL152H7/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Proteomic analysis of advanced colorectal cancer by laser capture microdissection and two-dimensiona...
Next Document:  Simultaneous electrochemical determination of arsenic, copper, lead and mercury in unpolluted fresh ...