Document Detail

Molecular biology of transposable elements.
MedLine Citation:
PMID:  3027015     Owner:  NLM     Status:  MEDLINE    
Transposable elements play an essential part in the epidemic spread of antibiotic resistances among bacterial populations. Their ubiquity and their role in the molecular evolution of genomes and organisms has captured the interest of molecular biologists, who investigate the genetic structure and novel mechanisms of recombination underlying transposition. This article, after introducing the general structure of mobile genetic elements and basic mechanistic concepts of transposition in bacteria, uses the well-studied Tn3 family as paradigm for gene organization, gene function and gene regulation. Finally, new applications of transposons in genetic engineering will be described.
R Schmitt
Related Documents :
24239855 - Nonsense-mediated mrna decay: inter-individual variability and human disease.
25116105 - Human fcr polymorphism and disease.
15659635 - Mx-rmx, a family of interacting transposons in the growing hat superfamily of maize.
7896105 - Mutator insertions in an intron of the maize knotted1 gene result in dominant suppressi...
20736745 - Nras mutations are rare in colorectal cancer.
14679585 - Genetic variants in zic1, zic2, and zic3 are not major risk factors for neural tube def...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Journal of antimicrobial chemotherapy     Volume:  18 Suppl C     ISSN:  0305-7453     ISO Abbreviation:  J. Antimicrob. Chemother.     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1987-03-03     Completed Date:  1987-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513617     Medline TA:  J Antimicrob Chemother     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  25-34     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
DNA Transposable Elements*
Genes, Bacterial
Reg. No./Substance:
0/DNA Transposable Elements

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Antibiotic resistance profiles and molecular epidemiology of Salmonella typhimurium and S. dublin, m...
Next Document:  Role of transposition and homologous recombination in the rearrangement of plasmid DNA.