Document Detail


Molecular biology of heart disease.
MedLine Citation:
PMID:  21526050     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Dr. Robert Roberts is currently Professor of Medicine and Director of the Ruddy Canadian Cardiovascular Genetics Centre along with being President and CEO of the University of Ottawa Heart Institute. Prior to this appointment, he was Chief of Cardiology for 23 years at Baylor College of Medicine, Houston, Texas. His original research was in cardiac enzymology which led to the development of the MBCK test which was the standard diagnostic assay for myocardial infarction for more than 3 decades. In the late 1970s, his research interests switched to molecular biology and the genetics of cardiomyopathies. He is regarded as one of the founders of molecular cardiology and has identified and sequenced more than 20 genes responsible for cardiovascular disorders. In the past 6 years, he has pursued genome-wide association studies to identify genes predisposing to coronary artery disease (CAD) and myocardial infarction. The first genetic variant for CAD, 9p21, was identified by Dr. Robert's laboratory and, in collaboration with the international consortium, CARDIoGRAM, has identified 13 novel genes for CAD.
Authors:
Robert Roberts
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of cardiology     Volume:  3     ISSN:  1949-8462     ISO Abbreviation:  World J Cardiol     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-28     Completed Date:  2011-05-12     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101537090     Medline TA:  World J Cardiol     Country:  China    
Other Details:
Languages:  eng     Pagination:  121-6     Citation Subset:  -    
Affiliation:
Robert Roberts, Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, Canada. rroberts@ottawaheart.ca
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